Protein Family Models for Protein (Select 489496832) - Protein Family Models

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Links from Protein

Items: 8

Select item 4122031.

This HMM identifies the P-loop-containing domain of large numbers of GTPases with ribosome-associated functions, including many involved in ribosome maturation (Der, Era, etc), ribosome rescue (HflX), and protein translation (InfB, Tuf, PrfC).

GO Terms:

Molecular Function:: GTP binding (GO:0005525)

Date:: 2024-10-16

Family Accession:: NF014036.5
Method:: HMM

Select item 4113682.

dynamin family protein

Date:: 2024-08-14

Family Accession:: NF012570.5
Method:: HMM

Select item 3896923.

new record, indexing in progress

Family Accession:

Select item 3884344.

new record, indexing in progress

Family Accession:

Select item 3476315.

new record, indexing in progress

Family Accession:

Select item 3464936.

new record, indexing in progress

Family Accession:

Select item 1920887.

isoniazid-induced dynamin-like GTPase IniC

Interruption of cell envelope biosynthesis pathways by either isoniazid or ethambutol, two unrelated front-line drugs for the treatment of tuberculosis, induces expression of the iniBAC operon, and mutational changes in any of the three encoded proteins can lead to adaptive resistance to those drugs. IniC, like IniA, is a dynamin-like GTPase, a member of a family involved in membrane remodeling events such as fusions and fissions during vesicle trafficking. A recent study on the adjacent protein IniA supports this view and weakens earlier suggestions that efflux might be the primary function of the operon.

Gene:: iniC

Date:: 2023-06-30

Family Accession:: NBR011042
Method:: BlastRule

Select item 512088.

dynamin-like GTPase family protein

dynamin-like GTPase family protein similar to Mycobacterium tuberculosis isoniazid-induced proteins IniA and IniC, and to Saccharomyces cerevisiae mitofusin FZO1, an essential transmembrane GTPase that mediates mitochondrial fusion