Protein Family Models for Protein (Select 489500371) - Protein Family Models

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Items: 5

Select item 4146641.

MazG nucleotide pyrophosphohydrolase domain-containing protein

This domain is about 100 amino acid residues in length. It is found in the MazG protein from E. coli. It contains four conserved negatively charged residues that probably form an active site or metal binding site. This domain is found in isolation in some proteins as well as associated with Pfam:PF00590. This domain is clearly related to Pfam:PF01503 another pyrophosphohydrolase involved in histidine biosynthesis. This family may be structurally related to the NUDIX domain Pfam:PF00293 (Bateman A pers. obs.). [1]. 12218018. MazG, a nucleoside triphosphate pyrophosphohydrolase, interacts with Era, an essential GTPase in Escherichia coli. Zhang J, Inouye M;. J Bacteriol 2002;184:5323-5329. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF015758.5
Method:: HMM

Select item 3906322.

new record, indexing in progress

Family Accession:

Select item 3504383.

new record, indexing in progress

Family Accession:

Select item 1805734.

nucleoside triphosphate pyrophosphohydrolase

Date:: 2020-10-26

Family Accession:: NF008987.0
Method:: HMM

Select item 607885.

MazG family protein

MazG family protein similar to nucleoside triphosphate pyrophosphohydrolase (NTP-PPase), which hydrolyzes all canonical (d)NTPs, as well as mutagenic dUTP and 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate (8-oxo-dGTP)