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OpcA/G6PD domain-containing protein
Members of this family are found in various prokaryotic OpcA and glucose-6-phosphate dehydrogenase proteins. This entry represents the C-terminal domain. (from Pfam)
glucose-6-phosphate dehydrogenase assembly protein OpcA
Members of this family are found in various prokaryotic OpcA and glucose-6-phosphate dehydrogenase proteins. This entry represents the N-terminal Rossmann like domain. (from Pfam)
glucose-6-phosphate dehydrogenase assembly protein OpcA may be involved in the functional assembly of glucose 6-phosphate dehydrogenase
The opcA gene is found immediately downstream of zwf, the glucose-6-phosphate dehydrogenase (G6PDH) gene, in a number of species, including Mycobacterium tuberculosis, Streptomyces coelicolor, Nostoc punctiforme, and Synechococcus sp. PCC 7942. In the latter, disruption of opcA was shown to block assembly of G6PDH into active oligomeric forms.
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