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NTF2-like N-terminal transpeptidase domain-containing protein
The structure of this domain from MecA is known [1] Swiss:Q53707 and is found to be similar to that found in NTF2 Pfam:PF02136. This domain seems unlikely to have an enzymatic function, and its role remains unknown. [1]. 12389036. Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus. Lim D, Strynadka NC;. Nat Struct Biol 2002;9:870-876. (from Pfam)
penicillin-binding transpeptidase domain-containing protein
The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family. [1]. 8605631. X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme. Pares S, Mouz N, Petillot Y, Hakenbeck R, Dideberg O. Nat Struct Biol 1996;3:284-289. (from Pfam)
MecA_N and FtsI domain-containing protein
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