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phosphopentomutase
phosphopentomutase catalyzes the interconversion of alpha-D-ribose 5-phosphate and alpha-D-ribose 1-phosphate
Metalloenzyme superfamily
This family includes phosphopentomutase Swiss:P07651 and 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, Swiss:P37689. This family is also related to Pfam:PF00245 [1]. The alignment contains the most conserved residues that are probably involved in metal binding and catalysis. [1]. 10082381. A superfamily of metalloenzymes unifies phosphopentomutase and cofactor- independent phosphoglycerate mutase with alkaline phosphatases and sulfatases. Galperin MY, Bairoch A, Koonin EV;. Protein Sci 1998;7:1829-1835. (from Pfam)
This protein is involved in the purine and pyrimidine salvage pathway. It catalyzes the conversion of D-ribose 1-phosphate to D-ribose 5-phosphate and the conversion of 2-deoxy-D-ribose 1-phosphate to 2-deoxy-D-ribose 5-phosphate. The seed members of this protein are characterized deoB proteins from E.Coli(SP:P07651) and Bacillus (SP:P46353). This HMM matches PF01676 for Metalloenzyme superfamily.
Catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose
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