Protein Family Models for Protein (Select 489529248) - Protein Family Models

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Links from Protein

Items: 7

Select item 4236921.

peptidoglycan binding domain-containing protein

This domain is found associated with the L,D-transpeptidase domain Pfam:PF03734. The structure of this domain has been solved and shows a mixed alpha-beta fold composed of nine beta strands and four alpha helices. This domain is usually found to be duplicated. Therefore, it seems likely that this domain acts to bind the two unlinked peptidoglycan chains and bring them into close association so they can be cross linked by the transpeptidase domain (Bateman A pers. observation). [1]. 16647082. Crystal structure of a novel beta-lactam-insensitive peptidoglycan transpeptidase. Biarrotte-Sorin S, Hugonnet JE, Delfosse V, Mainardi JL, Gutmann L, Arthur M, Mayer C;. J Mol Biol. 2006;359:533-538. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF023650.5
Method:: HMM

Select item 4152412.

VanW family protein

Family members include vancomycin resistance protein W (VanW). Genes encoding members of this family have been found in vancomycin resistance gene clusters vanB [1] and vanG [2]. The function of VanW is unknown. [1]. 11376048. High prevalence of VanB2 vancomycin-resistant Enterococcus faecium in Taiwan. Lu JJ, Perng CL, Ho MF, Chiueh TS, Lee WH;. J Clin Microbiol 2001;39:2140-2145. [2]. 11036060. Genetic characterization of vanG, a novel vancomycin resistance locus of Enterococcus faecalis. McKessar SJ, Berry AM, Bell JM, Turnidge JD, Paton JC;. Antimicrob Agents Chemother 2000;44:3224-3228. (from Pfam)