Protein Family Models

E. coli YceI is a base-induced periplasmic protein [1]. The recent structure of a member of this family shows that it binds to poly-isoprenoid [2]. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold. [1]. 12107143. pH-Dependent Expression of Periplasmic Proteins and Amino Acid Catabolism in Escherichia coli. Stancik LM, Stancik DM, Schmidt B, Barnhart DM, Yoncheva YN, Slonczewski JL;. J Bacteriol 2002;184:4246-4258. [2]. 15741337. Crystal structure of a novel polyisoprenoid-binding protein from Thermus thermophilus HB8. Handa N, Terada T, Doi-Katayama Y, Hirota H, Tame JR, Park SY, Kuramitsu S, Shirouzu M, Yokoyama S;. Protein Sci. 2005;14:1004-1010. (from Pfam)

Date:

2024-10-16

YceI family protein is a bacterial lipocalin (BCN), a small protein widely conserved in Gram-negative and Gram-positive bacteria whose physiological role is unclear; may be binding polyisoprenoids

Date:

2024-04-25