Protein Family Models

Pantoate-beta-alanine ligase, also know as pantothenate synthase, (EC:6.3.2.1) catalyses the formation of pantothenate from pantoate and alanine [1]. [1]. 374975. Pantothenate synthetase from Escherichia coli [D-pantoate: beta-alanine ligase (AMP-forming), EC 6.3.2.1]. Miyatake K, Nakano Y, Kitaoka S;. Methods Enzymol 1979;62:215-219. (from Pfam)

Date:

2024-10-16

4-phosphopantoate--beta-alanine ligase catalyzes the conversion of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway

Date:

2024-08-09

Protein families that contain at least one copy of this domain include citrate lyase ligase, pantoate-beta-alanine ligase, glycerol-3-phosphate cytidyltransferase, ADP-heptose synthase, phosphocholine cytidylyltransferase, lipopolysaccharide core biosynthesis protein KdtB, the bifunctional protein NadR, and a number whose function is unknown. Many of these proteins are known to use CTP or ATP and release pyrophosphate.

Date:

2024-05-30

This type of pantothenate synthetase, EC 6.3.2.1, is found in bacteria, and is unrelated to an archaeal form, EC 6.3.2.44 (see PRK13761).

Gene:

panC

Date:

2023-12-19