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leader peptide SpeFL
SpeFL is a small protein (arrest peptide) encoded upstream of inducible ornithine carboxylase gene (speF) that controls expression of downstream genes (speF and patE) by nascent chain-translational arrest and transcriptional attenuation. Ornithine capture by a translating ribosome controls bacterial polyamine synthesis, inducing the expression of ornithine decarboxylase SpeF4, in a mechanism involving ribosome stalling and transcription antitermination [1] [1]. 32094585. Ornithine capture by a translating ribosome controls bacterial polyamine synthesis. Herrero Del Valle A, Seip B, Cervera-Marzal I, Sacheau G, Seefeldt AC, Innis CA;. Nat Microbiol. 2020;5:554-561. (from Pfam)
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