Protein Family Models

Date:

2024-08-14

This family has similarities to the fusaric acid resistance protein family. The proteins are lodged in the inner membrane. [1]. 15919996. Global topology analysis of the Escherichia coli inner membrane proteome. Daley DO, Rapp M, Granseth E, Melen K, Drew D, von Heijne G;. Science. 2005;308:1321-1323. (from Pfam)

Date:

2024-10-16

This family includes a conserved region found in two proteins associated with fusaric acid resistance, Swiss:P24128 from Burkholderia cepacia[1] and Swiss:Q48403 from Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins. [1]. 1370369. Molecular cloning and characterization of the fusaric acid-resistance gene from Pseudomonas cepacia. Utsumi R, Yagi T, Katayama S, Katsuragi K, Tachibana K, Toyoda H, Ouchi S, Obata K, Shibano Y, Noda M;. Agric Biol Chem 1991;55:1913-1918. (from Pfam)

Date:

2024-10-16

This model represents two clades of putative transmembrane proteins including the E. coli YccS and YhfK proteins. The YccS hypothetical equivalog (TIGR01666) is found in beta and gamma proteobacteria, while the smaller YhfK group is only found in E. coli, Salmonella and Yersinia. TMHMM [1,2] on the 19 hits to this model shows a consensus of 11 transmembrane helices separated into two clusters, an N-terminal cluster of 6 and a central cluster of 5. This would indicate two non-membrane domains one on each side of the membrane

Date:

2021-10-21