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methyltransferase domain-containing protein
This family appears to be a methyltransferase domain. (from Pfam)
methyltransferase
Members of this family are SAM dependent methyltransferases. (from Pfam)
class I SAM-dependent methyltransferase
This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyse the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid. [1]. 8917504. A common mechanism for the biosynthesis of methoxy and cyclopropyl mycolic acids in Mycobacterium tuberculosis. Yuan Y, Barry CE 3rd;. Proc Natl Acad Sci U S A 1996;93:12828-12833. [2]. 7592990. The biosynthesis of cyclopropanated mycolic acids in Mycobacterium tuberculosis. Identification and functional analysis of CMAS-2. George KM, Yuan Y, Sherman DR, Barry CE 3d;. J Biol Chem 1995;270:27292-27298. [3]. 10882107. A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosis. Glickman MS, Cox JS, Jacobs WR Jr;. Mol Cell. 2000;5:717-727. (from Pfam)
SAM-dependent methyltransferase
SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor
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