Protein Family Models for Protein (Select 490220282) - Protein Family Models

Select item 4117741.

winged helix-turn-helix domain-containing protein

GO Terms:

Biological Process:: phosphorelay signal transduction system (GO:0000160)

Molecular Function:: DNA binding (GO:0003677)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Date:: 2024-08-14

Family Accession:: NF012698.5
Method:: HMM

Select item 4109172.

response regulator

This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. [1]. 7699720. Response regulators of bacterial signal transduction systems: selective domain shuffling during evolution. Pao GM, Saier MH;. J Mol Evol 1995;40:136-154. (from Pfam)

GO Terms:

Biological Process:: phosphorelay signal transduction system (GO:0000160)

Date:: 2024-10-16

Family Accession:: NF012301.5
Method:: HMM

Select item 3899573.

new record, indexing in progress

Family Accession:

Select item 3886044.

new record, indexing in progress

Family Accession:

Select item 3468575.

new record, indexing in progress

Family Accession:

Select item 3464746.

new record, indexing in progress

Family Accession:

Select item 2984797.

copper/silver response regulator transcription factor

Characterized members of this family are response regulator transcription factors involved in resistance to copper and/or silver, and have been assigned gene symbols such as CusR and SilR

Date:: 2021-07-22

Family Accession:: NF007346.1
Method:: HMM

Select item 2159008.

response regulator transcription factor CusR

two-component system response regulator transcription factor CusR binds DNA upon phosphorylation and functions as transcriptional regulator as part of the CusS/CusR system that is involved in response to copper and silver

Date:: 2018-12-03

Family Accession:: 11484500
Method:: Sparcle

Select item 1415519.

heavy metal response regulator transcription factor

Members of this family contain a response regulator receiver domain (Pfam:PF00072) and an associated transcriptional regulatory region (Pfam:PF00486). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc. Most members encoded by genes adjacent to genes for encoding a member of the heavy metal sensor histidine kinase family (TIGRFAMs:TIGR01386), its partner in the two-component response regulator system.

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Date:: 2021-08-05

Family Accession:: TIGR01387.1
Method:: HMM

Select item 8441210.

copper/silver response regulator transcription factor SilR

The heavy metal response regulator SilR, a DNA-binding transcription factor, belongs to a two-component system with the sensor histidine kinase SilS. The pair is found in plasmids, frequently in a Copper Homeostasis and Silver Resistance Island (CHASRI) locus. Although most strains of Klebsiella remain sensitive to high levels of silver as used in the topical treatment of burns, a single amino acid mutation of the SilS partner results in clinical results in resistance. SilR is closely related to the chromosomal copper response regulator CusR, as found on the chromosome of E. coli K-12.

Gene:: silR

Date:: 2019-01-09

Family Accession:: NBR007870
Method:: BlastRule

Select item 1959711.

new record, indexing in progress

Family Accession:

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