Protein Family Models for Protein (Select 490257590) - Protein Family Models

Select item 4226771.

Glutathione S-transferase, N-terminal domain

This family is closely related to Pfam:PF02798. (from Pfam)

GO Terms:

Molecular Function:: protein binding (GO:0005515)

Biological Process:: glutathione metabolic process (GO:0006749)

Date:: 2024-08-14

Family Accession:: NF024801.5
Method:: HMM

Select item 4217822.

glutathione S-transferase N-terminal domain-containing protein

GO Terms:

Molecular Function:: protein binding (GO:0005515)

Biological Process:: glutathione metabolic process (GO:0006749)

Date:: 2024-08-14

Family Accession:: NF024809.5
Method:: HMM

Select item 4114403.

glutaredoxin domain-containing protein

GO Terms:

Molecular Function:: protein-disulfide reductase activity (GO:0015035)

Date:: 2024-08-14

Family Accession:: NF012675.5
Method:: HMM

Select item 4029944.

new record, indexing in progress

Family Accession:

Select item 3996875.

new record, indexing in progress

Family Accession:

Select item 3883116.

new record, indexing in progress

Family Accession:

Select item 3636897.

new record, indexing in progress

Family Accession:

Select item 3481168.

new record, indexing in progress

Family Accession:

Select item 1750919.

glutaredoxin 3

Gene:: grxC

Date:: 2020-10-26

Family Accession:: NF007923.0
Method:: HMM

Select item 14228710.

glutaredoxin 3

Glutaredoxins are thioltransferases (disulfide reductases) which utilize glutathione and NADPH as cofactors. Oxidized glutathione is regenerated by glutathione reductase. Together these components compose the glutathione system [1]. Glutaredoxins utilize the CXXC motif common to thioredoxins and are involved in multiple cellular processes including protection from redox stress, reduction of critical enzymes such as ribonucleotide reductase and the generation of reduced sulfur for iron sulfur cluster formation. Glutaredoxins are capable of reduction of mixed disulfides of glutathione as well as the formation of glutathione mixed disulfides. This family of glutaredoxins includes the E. coli protein GrxC (Grx3) which appears to have a secondary role in reducing ribonucleotide reductase (in the absence of GrxA) possibly indicating a role in the reduction of other protein disulfides [2].

Gene:: grxC

GO Terms:

Biological Process:: cell redox homeostasis (GO:0045454)

Date:: 2024-06-24

Family Accession:: TIGR02181.1
Method:: HMM

Select item 10815311.

glutaredoxin

glutathione dependent reductase glutaredoxin

Date:: 2016-05-13

Family Accession:: 10793433
Method:: Sparcle

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