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MerR family transcriptional regulator
TipAS antibiotic-recognition domain-containing protein
This domain is found at the C-terminus of some MerR family transcription factors. The domain has an alpha-helical globin-like fold [1]. The family includes Mta a central regulator of multidrug resistance in Bacillus subtilis. [1]. 12682015. Structural basis for antibiotic recognition by the TipA class of multidrug-resistance transcriptional regulators. Kahmann JD, Sass HJ, Allan MG, Seto H, Thompson CJ, Grzesiek S;. EMBO J 2003;22:1824-1834. (from Pfam)
MerR family DNA-binding protein
Members of this family of DNA-binding domains are predominantly found in the prokaryotic transcriptional regulator MerR. They adopt a structure consisting of a core of three alpha helices, with an architecture that is similar to that of the 'winged helix' fold [1]. [1]. 12958362. Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR. Changela A, Chen K, Xue Y, Holschen J, Outten CE, O'Halloran TV, Mondragon A;. Science. 2003;301:1383-1387. (from Pfam)
MerR family DNA-binding transcriptional regulator
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