Protein Family Models for Protein (Select 490310495) - Protein Family Models

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Links from Protein

Items: 7

Select item 4231391.

These proteins catalyse the reversible transfer of an amino group from the amino acid substrate to an acceptor alpha-keto acid. They require pyridoxal 5'-phosphate (PLP) as a cofactor to catalyse this reaction. Trans-amination reactions are of central importance in amino acid metabolism and in links to carbohydrate and fat metabolism. This class of amino-transferases acts as dimers in a head-to-tail configuration. It has been demonstrated that these proteins are aspartate amino-transferases from Bacteria (Jansen, R.S. et al. Nat Commun 11, 1960 (2020)) [1]. [1]. 27355211. Structural Insights into a Novel Class of Aspartate Aminotransferase from Corynebacterium glutamicum. Son HF, Kim KJ;. PLoS One. 2016;11:e0158402. (from Pfam)

GO Terms:

Molecular Function:: L-aspartate:2-oxoglutarate aminotransferase activity (GO:0004069)

Date:: 2024-10-16

Family Accession:: NF024301.5
Method:: HMM

Select item 4110372.

aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme

GO Terms:

Biological Process:: biosynthetic process (GO:0009058)

Molecular Function:: pyridoxal phosphate binding (GO:0030170)

Date:: 2024-08-14

Family Accession:: NF012382.5
Method:: HMM

Select item 3994453.

new record, indexing in progress

Family Accession:

Select item 3884944.

new record, indexing in progress

Family Accession:

Select item 3636585.

new record, indexing in progress

Family Accession:

Select item 3481696.

new record, indexing in progress

Family Accession:

Select item 534587.

PLP-dependent aminotransferase family protein

pyridoxal phosphate (PLP)-dependent aminotransferase family protein may catalyze the reversible exchange of an amino group from one molecule with a keto group from another molecule