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PTS glucitol/sorbitol transporter subunit IIA
This entry consists of glucitol-specific transporters, and occur both in Gram-negative and Gram-positive bacteria. The system in Escherichia coli consists of a IIA protein and a IIBC protein. This family is specific for the IIA component. (from Pfam)
Involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
PTS glucitol/sorbitol transporter subunit IIA is a component of the glucitol/sorbitol-specific phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system that catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
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