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uL22 family ribosomal protein
This family includes L22 from prokaryotes and chloroplasts and L17 from eukaryotes. [1]. 9862810. The crystal structure of ribosomal protein L22 from Thermus thermophilus: insights into the mechanism of erythromycin resistance. Unge J, berg A, Al-Kharadaghi S, Nikulin A, Nikonov S, Davydova N, Nevskaya N, Garber M, Liljas A;. Structure 1998;6:1577-1586. (from Pfam)
50S ribosomal protein L22
50S ribosomal protein L22 binds specifically to 23S rRNA and is important during the early stages of 50S assembly
L22 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center. This model describes bacterial and chloroplast forms of ribosomal protein L22.
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