Protein Family Models for Protein (Select 490570981) - Protein Family Models

Select item 4223141.

substrate-binding domain-containing protein

This domain is found in a variety of bacterial periplasmic binding proteins. This domain recognises fructose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043). (from Pfam)

Date:: 2024-08-14

Family Accession:: NF024799.5
Method:: HMM

Select item 4118352.

Periplasmic binding proteins and sugar binding domain of LacI family

This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. The periplasmic binding proteins are the primary receptors for chemotaxis and transport of many sugar based solutes. The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain (Pfam:PF00356). [1]. 1583688. 1.7 A X-ray structure of the periplasmic ribose receptor from Escherichia coli. Mowbray SL, Cole LB;. J Mol Biol 1992;225:155-175. [2]. 8638105. Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Lewis M, Chang G, Horton NC, Kercher MA, Pace HC, Schumacher MA, Brennan RG, Lu P;. Science 1996;271:1247-1254. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF012742.5
Method:: HMM

Select item 4019493.

new record, indexing in progress

Family Accession:

Select item 3900874.

new record, indexing in progress

Family Accession:

Select item 3561785.

new record, indexing in progress

Family Accession:

Select item 3474616.

new record, indexing in progress

Family Accession:

Select item 510667.

rhamnose ABC transporter substrate-binding protein

This sugar-binding component of ABC transporter complexes is found in rhamnose catabolism operon contexts. Mutation of this gene in Rhizobium leguminosarum [1] abolishes rhamnose transport and prevents growth on rhamnose as a carbon source.

Gene:: rhaS

GO Terms:

Molecular Function:: rhamnose transmembrane transporter activity (GO:0015153)

Biological Process:: rhamnose transmembrane transport (GO:0015762)

Cellular Component:: outer membrane-bounded periplasmic space (GO:0030288)

Molecular Function:: rhamnose binding (GO:0033296)

Cellular Component:: ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing (GO:0055052)

Date:: 2024-07-12

Family Accession:: TIGR02637.1
Method:: HMM

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