Protein Family Models for Protein (Select 490723200) - Protein Family Models

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Items: 4

Select item 4139491.

rod shape-determining protein MreD

MreD (murein formation D) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped. (from Pfam)

Gene:: mreD

GO Terms:

Biological Process:: regulation of cell shape (GO:0008360)

Cellular Component:: membrane (GO:0016020)

Date:: 2024-08-14

Family Accession:: NF016019.5
Method:: HMM

Select item 3921092.

new record, indexing in progress

Family Accession:

Select item 3495583.

new record, indexing in progress

Family Accession:

Select item 1471184.

rod shape-determining protein MreD

Members of this protein family are the MreD protein of bacterial cell shape determination. Most rod-shaped bacteria depend on MreB and RodA to achieve either a rod shape or some other non-spherical morphology such as coil or stalk formation. MreD is encoded in an operon with MreB, and often with RodA and PBP-2 as well. It is highly hydrophobic (therefore somewhat low-complexity) and highly divergent, and therefore sometimes tricky to discover by homology, but this model finds most examples.