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6-carboxytetrahydropterin synthase
6-Pyruvoyl tetrahydrobiopterin synthase catalyses the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin, the second of three enzymatic steps in the synthesis of tetrahydrobiopterin from GTP. The functional enzyme is a hexamer of identical subunits [1]. [1]. 8137809. Three-dimensional structure of 6-pyruvoyl tetrahydropterin synthase, an enzyme involved in tetrahydrobiopterin biosynthesis. Nar H, Huber R, Heizmann CW, Thony B, Burgisser D;. EMBO J 1994;13:1255-1262. (from Pfam)
6-pyruvoyl trahydropterin synthase family protein
6-pyruvoyl tetrahydropterin synthase (PTPS) family protein similar to 6-carboxy-5,6,7,8-tetrahydropterin synthase that catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde, and dihydroneopterin monophosphate aldolase that catalyzes the conversion of 7,8-dihydroneopterin monophosphate (H2NMP) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD)
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