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TRAP transporter large permease subunit
This family contains a diverse range of predicted transporter proteins. Including the DctM subunit of the bacterial and archaeal TRAP C4-dicarboxylate transport (Dct) system permease. In general, C4-dicarboxylate transport systems allow C4-dicarboxylates like succinate, fumarate, and malate to be taken up. TRAP C4-dicarboxylate carriers are secondary carriers that use an electrochemical H+ gradient as the driving force for transport. DctM is an integral membrane protein that is one of the constituents of TRAP carriers [1]. Note that many family members are hypothetical proteins. [1]. 11803016. C4-dicarboxylate carriers and sensors in bacteria.. Janausch IG, Zientz E, Tran QH, Kroger A, Unden G;. Biochim Biophys Acta 2002;1553:39-56. (from Pfam)
SLC13 family permease
The SLC13 family permease is also known as DASS (Divalent Anion:Na+ Symporter). Characterized members are symporters of a substrate anion with sodium cations.
anion permease
There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1. (from Pfam)
SLC13 (solute carrier 13) family permease is a sodium-coupled symporter that facilitates the transport across biological membranes of various ions including sulfate or Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate
DASS family sodium-coupled anion symporter
DASS (Divalent Anion:Sodium(+) Symporter) transporters include Na(+)-coupled transporters of organic di- and tricarboxylates, inorganic phosphate, and inorganic sulfate. The family is designated 2.A.47 by the Transporter Classification Database.
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