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7TM domain-containing protein
A family of seven transmembrane helices fused to an inactive transglutaminase domain. The transglutaminase domain is predicted to be extracellularly located. Members of this family are associated in gene neighborhoods with a pepsin-like peptidase and an ATP-grasp of the RimK-family. The ATP-grasp is predicted to modify the 7TM protein or a cofactor that interacts with it [1]. [1]. 20023723. Amidoligases with ATP-grasp, glutamine synthetase-like and acetyltransferase-like domains: synthesis of novel metabolites and peptide modifications of proteins. Iyer LM, Abhiman S, Maxwell Burroughs A, Aravind L;. Mol Biosyst. 2009;5:1636-1660. (from Pfam)
UUP1 family membrane protein
Proteins of this family usually have a single N-terminal transmembrane domain followed by a hydrophilic domain and C-terminal 6 transmembrane domains. TCDB annotates them as ubiquitous uncharacterized 7 TMS protein-1(UUP1) family proteins (http://www.tcdb.org/search/result.php?tc=9.B.237).
inactive transglutaminase family protein
inactive transglutaminase family protein fused to 7 transmembrane helices may be associated in gene neighborhoods with a pepsin-like peptidase and an ATP-grasp of the RimK-family
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