Protein Family Models for Protein (Select 492435023) - Protein Family Models

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Links from Protein

Items: 6

Select item 4220701.

tetratricopeptide repeat protein

Date:: 2024-08-14

Family Accession:: NF024821.5
Method:: HMM

Select item 4217492.

CDC27 family protein

Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes [1, 2]. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20 [3]. [1]. 12049731. The anaphase-promoting complex: proteolysis in mitosis and beyond. Peters JM;. Mol Cell. 2002;9:931-943. [2]. 16896351. The anaphase promoting complex/cyclosome: a machine designed to destroy. Peters JM;. Nat Rev Mol Cell Biol. 2006;7:644-656. [3]. 12956947. TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1. Vodermaier HC, Gieffers C, Maurer-Stroh S, Eisenhaber F, Peters JM;. Curr Biol. 2003;13:1459-1468. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF024299.5
Method:: HMM

Select item 4014833.

new record, indexing in progress

Family Accession:

Select item 3993484.

new record, indexing in progress

Family Accession:

Select item 3583165.

new record, indexing in progress

Family Accession:

Select item 2083856.

tetratricopeptide repeat protein

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes