Protein Family Models for Protein (Select 493160967) - Protein Family Models

Select item 4223201.

Date:: 2024-08-14

Family Accession:: NF024923.5
Method:: HMM

Select item 4135352.

This family represents a small domain of the E2 subunit of 2-oxo-acid dehydrogenases responsible for the binding of the E3 subunit. [1]. 8805537. Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase. Mande SS, Sarfaty S, Allen MD, Perham RN, Hol WG;. Structure 1996;4:277-286. (from Pfam)

GO Terms:

Molecular Function:: acyltransferase activity (GO:0016746)

Date:: 2024-10-16

Family Accession:: NF014832.5
Method:: HMM

Select item 4113133.

2-oxo acid dehydrogenase subunit E2

These proteins contain one to three copies of a lipoyl binding domain followed by the catalytic domain. [1]. 8487300. Refined crystal structure of the catalytic domain of dihysrolipoyl transacetylase (E2P) from azotobacter vineelandii at 2.6 angstroms resolution. Mattevi A, Obmolova G, Kalk KH, Westphal AH, De Kok A, Hol WG;. J Mol Biol 1993;230:1183-1199. (from Pfam)

GO Terms:

Molecular Function:: acyltransferase activity (GO:0016746)

Date:: 2024-10-29

Family Accession:: NF012424.5
Method:: HMM

Select item 4109984.

biotin/lipoyl-containing protein

This family covers two Prosite entries, the conserved lysine residue binds biotin in one group and lipoic acid in the other. Note that the HMM does not currently recognise the Glycine cleavage system H proteins. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF012584.5
Method:: HMM

Select item 4002045.