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CusS sensor domain
This entry represents a periplasmic sensor domain found in CusS from E. coli [1]. The overall structure of the domain shows a PAS like topology. Paper describing PDB structure 5ku5. [1]. 27583660. The Structure of the Periplasmic Sensor Domain of the Histidine Kinase CusS Shows Unusual Metal Ion Coordination at the Dimeric Interface. Affandi T, Issaian AV, McEvoy MM;. Biochemistry. 2016;55:5296-5306. (from Pfam)
GHKL domain-containing protein
This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90. (from Pfam)
ATP-binding protein
This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90. [1]. 18361456. Crystal structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source. Li Y, Bahti P, Shaw N, Song G, Chen S, Zhang X, Zhang M, Cheng C, Yin J, Zhu JY, Zhang H, Che D, Xu H, Abbas A, Wang BC, Liu ZJ;. Proteins 2008;71:2109-13. (from Pfam)
HAMP domain-containing protein
histidine kinase dimerization/phospho-acceptor domain-containing protein
Dimerisation and phospho-acceptor domain of histidine kinases. [1]. 9989504. Structure of CheA, a signal-transducing histidine kinase. Bilwes AM, Alex LA, Crane BR, Simon MI;. Cell 1999;96:131-141. [2]. 18361456. Crystal structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source. Li Y, Bahti P, Shaw N, Song G, Chen S, Zhang X, Zhang M, Cheng C, Yin J, Zhu JY, Zhang H, Che D, Xu H, Abbas A, Wang BC, Liu ZJ;. Proteins 2008;71:2109-13. (from Pfam)
heavy metal sensor histidine kinase
Members of this family contain a sensor histidine kinase domain (Pfam:PF00512) and a domain found in bacterial signal proteins (Pfam:PF00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
sensor histidine kinase
sensor histidine kinase with a HAMP signaling domain, part of a two-component regulatory system, functions as a protein kinase that phosphorylates a target protein in response to various signals
copper resistance membrane spanning protein PcoS
PcoS interacts with PcoR as part of a two-component response regulator system that affects Cu+2 resistance.
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