Protein Family Models for Protein (Select 494113144) - Protein Family Models

Select item 4236331.

substrate-binding domain-containing protein

This domain is found in a variety of transcriptional regulatory proteins. It is related to bacterial periplasmic binding proteins, although this domain is unlikely to be found in the periplasm. This domain acts as a sensor binding small molecule ligands that the DNA-binding domain responds to. This domain recognises Sugars, sugar phosphates, sugar acids and purines (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043). (from Pfam)

Date:: 2024-08-14

Family Accession:: NF024770.5
Method:: HMM

Select item 4183282.

bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase

This enzyme EC:2.7.4.7 is part of the Thiamine pyrophosphate (TPP) synthesis pathway, TPP is an essential cofactor for many enzymes [1]. [1]. 9244280. Identification and characterization of an operon in Salmonella typhimurium involved in thiamine biosynthesis. Petersen LA, Downs DM;. J Bacteriol 1997;179:4894-4900. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF020132.5
Method:: HMM

Select item 4119863.

LacI family DNA-binding transcriptional regulator

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Date:: 2024-08-14

Family Accession:: NF012576.5
Method:: HMM

Select item 4109284.

PfkB family carbohydrate kinase

This family includes a variety of carbohydrate and pyrimidine kinases. [1]. 9519409. Identification and characterization of an operon in Salmonella typhimurium involved in thiamine biosynthesis. Petersen LA, Downs DM;. J Bacteriol 1997;179:4894-4900. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF012515.5
Method:: HMM

Select item 4004805.