Protein Family Models for Protein (Select 495644966) - Protein Family Models

Select item 4263201.

methyltransferase domain-containing protein

This family appears to have methyltransferase activity. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF025217.5
Method:: HMM

Select item 4232842.

methyltransferase domain-containing protein

This family appears to be a methyltransferase domain. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF025033.5
Method:: HMM

Select item 4170093.

class I SAM-dependent methyltransferase

This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF018645.5
Method:: HMM

Select item 4131604.

16S rRNA (cytosine(1402)-N(4))-methyltransferase

Members of this family are probably SAM dependent methyltransferases based on Swiss:P18595 [1]. This family appears to be related to Pfam:PF01596. [1]. 10572301. mraW, an essential gene at the dcw cluster of Escherichia coli codes for a cytoplasmic protein with methyltransferase activity. Carrion M, Gomez MJ, Merchante-Schubert R, Dongarra S, Ayala JA;. Biochimie 1999;81:879-888. (from Pfam)

Gene:: mraW

GO Terms:

Molecular Function:: methyltransferase activity (GO:0008168)

Date:: 2024-10-16

Family Accession:: NF013919.5
Method:: HMM

Select item 4123975.

SAM-dependent methyltransferase

This family consists of FtsJ from various bacterial and archaeal sources FtsJ is a methyltransferase, but actually has no effect on cell division. FtsJ's substrate is the 23S rRNA. The 1.5 A crystal structure of FtsJ in complex with its cofactor S-adenosylmethionine revealed that FtsJ has a methyltransferase fold. This family also includes the N terminus of flaviviral NS5 protein. It has been hypothesised that the N-terminal domain of NS5 is a methyltransferase involved in viral RNA capping [2]. [1]. 10983982. RNA methylation under heat shock control. Bugl H, Fauman EB, Staker BL, Zheng F, Kushner SR, Saper MA, Bardwell JC, Jakob U;. Mol Cell 2000;6:349-360. [2]. 8385698. Computer-assisted identification of a putative methyltransferase domain in NS5 protein of flaviviruses and lambda 2 protein of reovirus. Koonin EV;. J Gen Virol 1993;74:733-740. (from Pfam)

GO Terms:

Molecular Function:: methyltransferase activity (GO:0008168)

Date:: 2024-10-16

Family Accession:: NF013856.5
Method:: HMM

Select item 4030096.