Protein Family Models for Protein (Select 495778089) - Protein Family Models

Select item 4110591.

This family includes permeases for diverse substrates such as xanthine Swiss:P42086, uracil Swiss:P39766 and vitamin C Swiss:Q9UGH3. However many members of this family are functionally uncharacterised and may transport other substrates. Members of this family have ten predicted transmembrane helices. (from Pfam)

GO Terms:

Cellular Component:: membrane (GO:0016020)

Molecular Function:: transmembrane transporter activity (GO:0022857)

Biological Process:: transmembrane transport (GO:0055085)

Date:: 2024-08-14

Family Accession:: NF013056.5
Method:: HMM

Select item 3887402.

new record, indexing in progress

Family Accession:

Select item 3471473.

new record, indexing in progress

Family Accession:

Select item 2618704.

nucleobase:cation symporter-2 family protein

nucleobase:cation symporter-2 (NCS2) family protein is involved in the transport of nucleobases, such as Escherichia coli xanthine permease XanQ

Date:: 2024-12-09

Family Accession:: 10795438
Method:: Sparcle

Select item 845585.

xanthine/proton symporter XanP

Gene:: xanP

Date:: 2019-02-19

Family Accession:: NBR008201
Method:: BlastRule

Select item 244446.

NCS2 family nucleobase:cation symporter

The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40) Most of the functionally characterized members of the NCS2 family are transporters specific for nucleobases including both purines and pyrimidines. However, two closely related rat members of the family, SVCT1 and SVCT2, localized to different tissues of the body, cotransport L-ascorbate and Na+ with a high degree of specificity and high affinity for the vitamin. The NCS2 family appears to be distantly related to the NCS1 family (TC #2.A.39).

GO Terms:

Molecular Function:: nucleobase transmembrane transporter activity (GO:0015205)

Biological Process:: nucleobase transport (GO:0015851)

Cellular Component:: membrane (GO:0016020)

Date:: 2022-10-11

Family Accession:: TIGR00801.1
Method:: HMM

Select item 222347.

purine/pyrimidine permease

Proteins of this family usually have 14 transmembrane domains. They belong to the NSC2 superfamily transporters. They are specific purine and/or pyrimidine permeases.

GO Terms:

Molecular Function:: transmembrane transporter activity (GO:0022857)

Biological Process:: transmembrane transport (GO:0055085)

Date:: 2022-03-28

Family Accession:: NF037981.1
Method:: HMM

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