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bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
This enzyme EC:2.7.4.7 is part of the Thiamine pyrophosphate (TPP) synthesis pathway, TPP is an essential cofactor for many enzymes [1]. [1]. 9244280. Identification and characterization of an operon in Salmonella. typhimurium involved in thiamine biosynthesis.. Petersen LA, Downs DM;. J Bacteriol 1997;179:4894-4900. (from Pfam)
PfkB family carbohydrate kinase
This family includes a variety of carbohydrate and pyrimidine kinases. [1]. 9519409. Identification and characterization of an operon in Salmonella. typhimurium involved in thiamine biosynthesis.. Petersen LA, Downs DM;. J Bacteriol 1997;179:4894-4900. (from Pfam)
ribokinase
ribokinase catalyzes the formation of D-ribose 5-phosphate from ribose
This HMM describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (PF00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not.
Catalyzes the formation of D-ribose 5-phosphate from ribose
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