Protein Family Models

FtsA is essential for bacterial cell division, and co-localises to the septal ring with FtsZ. It has been suggested that the interaction of FtsA-FtsZ has arisen through coevolution in different bacterial strains [1]. The FtsA protein contains two structurally related actin-like ATPase domains which are also structurally related to the ATPase domains of HSP70 (see PF00012). FtsA has a SHS2 domain PF02491 inserted in to the RnaseH fold PF02491 [2]. [1]. 9352931. Interactions between heterologous FtsA and FtsZ proteins at the FtsZ ring. Ma X, Sun Q, Wang R, Singh G, Jonietz EL, Margolin W;. J Bacteriol 1997;179:6788-6797. [2]. 15281131. The SHS2 module is a common structural theme in functionally diverse protein groups, like Rpb7p, FtsA, GyrI, and MTH1598/TM1083 superfamilies. Anantharaman V, Aravind L;. Proteins. 2004;56:795-807. (from Pfam)

Date:

2024-10-16

The type IV pilus assembly protein PilM is required for competency and pilus biogenesis [1-2]. It binds to PilN and ATP [3]. [1]. 8550460. Characterization of genes required for pilus expression in Pseudomonas syringae pathovar phaseolicola. Roine E, Nunn DN, Paulin L, Romantschuk M;. J Bacteriol. 1996;178:410-417. [2]. 16857013. Identification, subcellular localization and functional interactions of PilMNOWQ and PilA4 involved in transformation competency and pilus biogenesis in the thermophilic bacterium Thermus thermophilus HB27. Rumszauer J, Schwarzenlander C, Averhoff B;. FEBS J. 2006;273:3261-3272. [3]. 21596754. Structure of the PilM-PilN inner membrane type IV pilus biogenesis complex from Thermus thermophilus. Karuppiah V, Derrick JP;. J Biol Chem. 2011;286:24434-24442. (from Pfam)

Gene:

pilM

Date:

2024-10-16

ethanolamine utilization protein EutJ

Date:

2020-10-22

Gene:

eutJ

Date:

2021-09-22

Date:

2019-09-10