Protein Family Models

LptE (formerly known as RplB) is involved in lipopolysaccharide-assembly on the outer membrane of Gram-negative organisms. The lipopolysaccharide component of the outer bacterial membrane is transported from its source of origin to the outer membrane by a set of proteins constituting a transport machinery that is made up of LptA, LptB, LptC, LptD, LptE. LptD appears to be anchored in the outer membrane, and LptE forms a complex with it. This part of the machinery complex is involved in the assembly of lipopolysaccharide in the outer leaflet of the outer membrane [1]. [1]. 18424520. Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli. Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A;. J Bacteriol. 2008;190:4460-4469. (from Pfam)

Gene:

lptE

Date:

2024-10-16

LPS-assembly lipoprotein LptE, together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane

Date:

2020-10-08

Gene:

lptE

Date:

2021-10-20