Protein Family Models

ThrE is a family of bacterial and Archaeal proteins that catalyse the export of L-threonine from the cell [1]. UniProtKB:Q79VD1 has been characterised as being necessary for this export. The domain exhibits 10 putative TMs and catalyses the proton-motive-force-dependent efflux of threonine and serine [2]. [1]. 12089010. Identification of glyA (encoding serine hydroxymethyltransferase) and its use together with the exporter ThrE to increase L-threonine accumulation by Corynebacterium glutamicum. Simic P, Willuhn J, Sahm H, Eggeling L;. Appl Environ Microbiol. 2002;68:3321-3327. [2]. 12111147. Influence of threonine exporters on threonine production in Escherichia coli. Kruse D, Kramer R, Eggeling L, Rieping M, Pfefferle W, Tchieu JH, Chung YJ, Jr Saier MH, Burkovski A;. Appl Microbiol Biotechnol. 2002;59:205-210. (from Pfam)

Date:

2024-10-16

threonine/serine exporter ThrE family protein similar to Escherichia coli inner membrane protein YjjP, which may function as a succinate transporter

Date:

2023-03-11