Rubrerythrin (RUBY) is a fusion protein containing an N-terminal diiron-binding domain (Pfam:PF02915) and a C-terminal rubredoxin-like domain. RUBY may play a role in oxidative stress. This entry represents the rubredoxin-like domain of RUBY and reverse rubrerythrin 1/2 from Clostridium acetobutylicum (RRBR1/2) [1-5]. RRBRs function as the terminal component of an NADH peroxidase when using NADH:rubredoxin oxidoreductase (NROR) as the electron transport intermediary from NADH to RRBRs and play an important role in the oxidative stress defense system of C. acetobutylicum [6]. Paper describing PDB structure 1b2j. [1]. 10216292. Rubredoxin from Clostridium pasteurianum. Structures of G10A, G43A and G10VG43A mutant proteins. Mutation of conserved glycine 10 to valine causes the 9-10 peptide link to invert. Maher MJ, Xiao Z, Wilce MC, Guss JM, Wedd AG;. Acta Crystallogr D Biol Crystallogr. 1999;55:962-968. Paper describing PDB structure 1b71. [2]. 10201393. Alternative metal-binding sites in rubrerythrin. Sieker LC, Holmes M, Le Trong I, Turley S, Santarsiero BD, Liu MY, LeGall J, Stenkamp RE;. Nat Struct Biol. 1999;6:308-309. Paper describing PDB structure 1c09. [3]. 10555962. Modulation of the redox potential of the [Fe(SCys)(4)] site in rubredoxin by the orientation of a peptide dipole. Eidsness MK, Burden AE, Richie KA, Kurtz DM Jr, Scott RA, Smith ET, Ichiye T, Beard B, Min T, Kang C;. Biochemistry. 1999;38:14803-14809. Paper describing PDB structure 1jyb. [4]. 12459910. Crystal structure studies on rubrerythrin: enzymatic activity in relation to the zinc movement. Li M, Liu MY, LeGall J, Gui LL, Liao J, Jiang T, . TRUNCATED at 1650 bytes (from Pfam)
GO Terms:- Date:
- 2024-10-16