Protein Family Models for Protein (Select 497332088) - Protein Family Models

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Items: 5

Select item 4145801.

UDP-3-O-acyl-N-acetylglucosamine deacetylase

The enzymes in this family catalyse the second step in the biosynthetic pathway for lipid A. [1]. 10753902. Antibacterial agents that target lipid A biosynthesis in gram-negative bacteria. Inhibition of diverse UDP-3-O-(r-3-hydroxymyristoyl)-n-acetylglucosamine deacetylases by substrate analogs containing zinc binding motifs. Jackman JE, Fierke CA, Tumey LN, Pirrung M, Uchiyama T, Tahir SH, Hindsgaul O, Raetz CR;. J Biol Chem 2000;275:11002-11009. (from Pfam)

GO Terms:

Biological Process:: lipid A biosynthetic process (GO:0009245)

Molecular Function:: UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (GO:0103117)

Date:: 2024-10-21

Family Accession:: NF015299.5
Method:: HMM

Select item 3898502.

new record, indexing in progress

Family Accession:

Select item 3487443.

new record, indexing in progress

Family Accession:

Select item 1756554.

UDP-3-O-acyl-N-acetylglucosamine deacetylase

UDP-3-O-acyl-N-acetylglucosamine deacetylase catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis

Date:: 2017-06-22

Family Accession:: 10002399
Method:: Sparcle

Select item 190625.

UDP-3-O-acyl-N-acetylglucosamine deacetylase

UDP-3-O-acyl-N-acetylglucosamine deacetylase from E. coli, LpxC, was previously designated EnvA. This enzyme is involved in lipid-A precursor biosynthesis. It is essential for cell viability.