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efflux RND transporter permease subunit
Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer [1]. [1]. 12374972. Crystal structure of bacterial multidrug efflux transporter AcrB. Murakami S, Nakashima R, Yamashita E, Yamaguchi A;. Nature 2002;419:587-593. (from Pfam)
Cu(+)/Ag(+) efflux RND transporter permease subunit SilA
CusA/CzcA family heavy metal efflux RND transporter
This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of Pfam HMM PF00873.
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