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Universal stress protein B (UspB)
UspB in Escherichia coli is a 14kDa protein which is predicted to be an integral membrane protein. Overexpression of UspB results in cell death in stationary phase, and mutants of uspB are sensitive to ethanol exposure during stationary phase [1]. [1]. 9829921. uspB, a new sigmaS-regulated gene in Escherichia coli which is required for stationary-phase resistance to ethanol. Farewell A, Kvint K, Nystrom T;. J Bacteriol. 1998;180:6140-6147. (from Pfam)
universal stress protein UspB
ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress
universal stress protein UspB is most likely an integral membrane protein that may play a role in sensing or mediating needed alterations in membrane composition during stationary phase
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