Protein Family Models

PFOR_II is a core domain of the anaerobic enzyme pyruvate:ferredoxin oxidoreductase and is necessary for inter subunit contacts in conjunction with domains I and IV [1,2]. [1]. 10048931. Crystal structures of the key anaerobic enzyme. pyruvate:ferredoxin oxidoreductase, free and in complex with. pyruvate.. Chabriere E, Charon MH, Volbeda A, Pieulle L, Hatchikian EC,. Fontecilla-Camps JC;. Nat Struct Biol 1999;6:182-190.. [2]. 20956531. Identification and characterization of oxalate oxidoreductase, a. novel thiamine pyrophosphate-dependent 2-oxoacid oxidoreductase. that enables anaerobic growth on oxalate.. Pierce E, Becker DF, Ragsdale SW;. J Biol Chem. 2010;285:40515-40524. (from Pfam)

Date:

2024-08-14

This family includes the N terminal structural domain of the pyruvate ferredoxin oxidoreductase. This domain binds thiamine diphosphate, and along with domains II and IV, is involved in inter subunit contacts [3]. The family also includes pyruvate flavodoxin oxidoreductase as encoded by the nifJ gene in cyanobacterium which is required for growth on molecular nitrogen when iron is limited [2]. [1]. 8550425. Molecular and phylogenetic characterization of pyruvate and. 2-ketoisovalerate ferredoxin oxidoreductases from Pyrococcus. furiosus and pyruvate ferredoxin oxidoreductase from Thermotoga. maritima.. Kletzin A, Adams MW;. J Bacteriol 1996;178:248-257.. [2]. 8415612. Growth of the cyanobacterium Anabaena on molecular nitrogen:. NifJ is required when iron is limited.. Bauer CC, Scappino L, Haselkorn R;. Proc Natl Acad Sci U S A 1993;90:8812-8816.. [3]. 10048931. Crystal structures of the key anaerobic enzyme. pyruvate:ferredoxin oxidoreductase, free and in complex with. pyruvate.. Chabriere E, Charon MH, Volbeda A, Pieulle L, Hatchikian EC,. Fontecilla-Camps JC;. Nat Struct Biol 1999;6:182-190. (from Pfam)

Date:

2024-08-14