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oligosaccharide flippase family protein
polysaccharide biosynthesis C-terminal domain-containing protein
This family represents the C-terminal integral membrane region of polysaccharide biosynthesis proteins. (from Pfam)
MATE family efflux transporter
MATE (Multi Antimicrobial Extrusion), 2.A.66.1 in Transporter Classification Database, is a widely distributed transporter family that includes both human proteins and bacterial antibiotic resistance efflux transporters.
Members of this family are integral membrane proteins [1]. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon [2]. The family includes SpoVB from Bacillus subtilis Swiss:Q00758, which is involved in spore cortex biosynthesis [3]. [1]. 8118055. Analysis of the Rhizobium meliloti genes exoU, exoV, exoW, exoT, and exoI involved in exopolysaccharide biosynthesis and nodule invasion: exoU and exoW probably encode glucosyltransferases. Becker A, Kleickmann A, Kuster H, Keller M, Arnold W, Puhler A;. Mol Plant Microbe Interact. 1993;6:735-744. [2]. 7517390. Genetic analysis of the O-specific lipopolysaccharide biosynthesis region (rfb) of Escherichia coli K-12 W3110: identification of genes that confer group 6 specificity to Shigella flexneri serotypes Y and 4a. Yao Z, Valvano MA;. J Bacteriol 1994;176:4133-4143. [3]. 1744050. Cloning, characterization, and expression of the spoVB gene of Bacillus subtilis. Popham DL, Stragier P;. J Bacteriol 1991;173:7942-7949. (from Pfam)
flippase
flippase assists in the membrane translocation of lipopolysaccharides including those containing O-antigens; similar to Escherichia coli O-antigen transporter
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