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Phe-tRNA synthetase beta subunit B1 domain
This is the N-terminal domain found in human cytosolic phenylalanyl tRNA synthetase beta subunit [1]. [1]. 20223217. Structure of human cytosolic phenylalanyl-tRNA synthetase:. evidence for kingdom-specific design of the active sites and. tRNA binding patterns.. Finarov I, Moor N, Kessler N, Klipcan L, Safro MG;. Structure. 2010;18:343-353. (from Pfam)
Phenylalanyl tRNA synthetase beta chain CLM domain
This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase [1]. [1]. 21082706. Idiosyncrasy and identity in the prokaryotic Phe-system: crystal. structure of E. coli phenylalanyl-tRNA synthetase complexed. with phenylalanine and AMP.. Mermershtain I, Finarov I, Klipcan L, Kessler N, Rozenberg H,. Safro MG;. Protein Sci. 2011;20:160-167. (from Pfam)
tRNA synthetase B5 domain
This domain is found in phenylalanine-tRNA synthetase beta subunits. [1]. 10447505. Evolution of aminoacyl-tRNA synthetases--analysis of unique. domain architectures and phylogenetic trees reveals a complex. history of horizontal gene transfer events.. Wolf YI, Aravind L, Grishin NV, Koonin EV;. Genome Res 1999;9:689-710. (from Pfam)
phenylalanine--tRNA ligase beta subunit-related protein
This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins. [1]. 10447505. Evolution of aminoacyl-tRNA synthetases--analysis of unique. domain architectures and phylogenetic trees reveals a complex. history of horizontal gene transfer events.. Wolf YI, Aravind L, Grishin NV, Koonin EV;. Genome Res 1999;9:689-710. (from Pfam)
tRNA synthetases class II core domain (F)
Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only phenylalanyl-tRNA synthetases. This is the core catalytic domain. (from Pfam)
similar to phenylalanine-tRNA ligase beta subunit
protein similar to phenylalanine-tRNA ligase beta subunit
phenylalanine--tRNA ligase subunit beta
Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This HMM represents the subfamily that includes the beta subunit from eukaryotic cytosol, the Archaea, and spirochetes.
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