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Links from Protein

Items: 5

1.

sarcosine oxidase subunit delta

Sarcosine oxidase is a hetero-tetrameric enzyme that contains both covalently bound FMN and non-covalently bound FAD and NAD(+). This enzyme catalyses the oxidative demethylation of sarcosine to yield glycine, H2O2, and 5,10-CH2-tetrahydrofolate (H4folate) in a reaction requiring H4folate and O2 [1,2]. [1]. 11330998. Organization of the multiple coenzymes and subunits and role of the covalent flavin link in the complex heterotetrameric sarcosine oxidase. Eschenbrenner M, Chlumsky LJ, Khanna P, Strasser F, Jorns MS;. Biochemistry 2001;40:5352-5367. [2]. 7543100. Sequence analysis of sarcosine oxidase and nearby genes reveals homologies with key enzymes of folate one-carbon metabolism. Chlumsky LJ, Zhang L, Jorns MS;. J Biol Chem 1995;270:18252-18259. (from Pfam)

GO Terms:
Molecular Function:
sarcosine oxidase activity (GO:0008115)
Biological Process:
tetrahydrofolate metabolic process (GO:0046653)
Date:
2024-10-16
Family Accession:
NF016179.5
Method:
HMM
2.
new record, indexing in progress
Family Accession:
3.
new record, indexing in progress
Family Accession:
4.

sarcosine oxidase subunit delta family protein

This HMM describes the delta subunit of a family of known and putative heterotetrameric sarcosine oxidases. Five operons of such oxidases are found in Mesorhizobium loti and three in Agrobacterium tumefaciens, a high enough copy number to suggest that not all members are share the same function. The model is designated as subfamily rather than equivalog for this reason. Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) form

Date:
2019-09-10
Family Accession:
TIGR01374.1
Method:
HMM
5.

sarcosine oxidase subunit delta

sarcosine oxidase subunit delta (SoxD) is part of the heterotetrameric enzyme that catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10-methylenetetrahydrofolate

Date:
2019-06-06
Family Accession:
10018820
Method:
Sparcle
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