Protein Family Models for Protein (Select 499270726) - Protein Family Models

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Links from Protein

Items: 5

Select item 4118371.

formyltransferase family protein

Many but not all members of this family are formyltransferases or deformylases, including hosphoribosylglycinamide formyltransferase 1 (EC 2.1.2.2), methionyl-tRNA formyltransferase (EC 2.1.2.9), and formyltetrahydrofolate deformylase (EC 3.5.1.1).

GO Terms:

Biological Process:: biosynthetic process (GO:0009058)

Molecular Function:: hydroxymethyl-, formyl- and related transferase activity (GO:0016742)

Date:: 2024-10-16

Family Accession:: NF012760.5
Method:: HMM

Select item 3900892.

new record, indexing in progress

Family Accession:

Select item 3470143.

new record, indexing in progress

Family Accession:

Select item 1584404.

formyltetrahydrofolate deformylase

Produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine

Date:: 2020-10-26

Family Accession:: NF004684.0
Method:: HMM

Select item 223965.

formyltetrahydrofolate deformylase

This HMM describes formyltetrahydrofolate deformylases. The enzyme is a homohexamer. Sequences from a related enzyme formyl tetrahydrofolate-specific enzyme, phosphoribosylglycinamide formyltransferase, serve as an outgroup for phylogenetic analysis. Putative members of this family, scoring below the trusted cutoff, include a sequence from Rhodobacter capsulatus that lacks an otherwise conserved C-terminal region.