Protein Family Models for Protein (Select 499403561) - Protein Family Models

Select item 4221721.

This is the catalytic domain of class A beta-lactamases [1]. It is closely related to Beta-lactamase, Pfam:PF00144, the serine beta-lactamase-like superfamily, which contains the distantly related Pfam:PF00905 and PF00768 D-alanyl-D-alanine carboxypeptidase. [1]. 19100272. Structure of PBP-A from Thermosynechococcus elongatus, a penicillin-binding protein closely related to class A beta-lactamases. Urbach C, Evrard C, Pudzaitis V, Fastrez J, Soumillion P, Declercq JP;. J Mol Biol. 2009;386:109-120. (from Pfam)

GO Terms:

Molecular Function:: beta-lactamase activity (GO:0008800)

Biological Process:: beta-lactam antibiotic catabolic process (GO:0030655)

Date:: 2024-10-16

Family Accession:: NF024748.5
Method:: HMM

Select item 4110862.

serine hydrolase

This model finds serine hydrolases of many sorts, including class C beta-lactamases. Despite the name given by Pfam as a short-hand for this HMM, members proteins should be assumed to be something other than a beta-lactamase if RefSeq or PGAP uses this HMM for naming. True beta-lactamases are named by more specific HMMs.

Date:: 2024-08-14

Family Accession:: NF012371.5
Method:: HMM

Select item 3995383.

new record, indexing in progress

Family Accession:

Select item 3886424.

new record, indexing in progress

Family Accession:

Select item 3636855.

new record, indexing in progress

Family Accession:

Select item 3465946.

new record, indexing in progress

Family Accession:

Select item 857847.

class A beta-lactamase-related serine hydrolase

class A beta-lactamase-related serine hydrolase, similar to beta lactamases which hydrolyze the amide bond of the beta-lactam ring via the formation of an acyl-enzyme covalent complex

Date:: 2024-08-05

Family Accession:: 11457170
Method:: Sparcle

Select item 350938.

CTX-M family extended-spectrum class A beta-lactamase

Gene:: blaCTX-M

GO Terms:

Molecular Function:: beta-lactamase activity (GO:0008800)

Date:: 2024-03-19

Family Accession:: NF033089.1
Method:: HMM

Select item 345819.

new record, indexing in progress

Family Accession:

Select item 2111210.

new record, indexing in progress

Family Accession:

Select item 2049811.

class A beta-lactamase

Gene:: bla

GO Terms:

Molecular Function:: beta-lactamase activity (GO:0008800)

Biological Process:: beta-lactam antibiotic catabolic process (GO:0030655)

Biological Process:: response to antibiotic (GO:0046677)

Date:: 2022-02-22

Family Accession:: NF033103.1
Method:: HMM

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