Protein Family Models

Members of the RdgC family may have exonuclease activity. RdgC is required for efficient pilin variation in Neisseria gonorrhoeae, suggesting that it may be involved in recombination reactions [1]. In Escherichia coli, RdgC is required for growth in recombination-deficient exonuclease-depleted strains. Under these conditions, RdgC may act as an exonuclease to remove collapsed replication forks, in the absence of the normal repair mechanisms [2]. [1]. 10655208. A homologue of the recombination-dependent growth gene, rdgC, is involved in gonococcal pilin antigenic variation. Mehr IJ, Long CD, Serkin CD, Seifert HS;. Genetics 2000;154:523-532. [2]. 8807285. Recombination-dependent growth in exonuclease-depleted recBC sbcBC strains of Escherichia coli K-12. Ryder L, Sharples GJ, Lloyd RG;. Genetics 1996;143:1101-1114. (from Pfam)

Gene:

rdgC

Date:

2024-10-16

recombination-associated protein RdgC plays a role in recombination and replication fork repair

Date:

2016-06-15

Gene:

rdgC

Date:

2020-10-26

Gene:

rdgC

Date:

2020-10-26