Protein Family Models

ZapA is a cell division protein which interacts with FtsZ. FtsZ is part of a mid-cell cytokinetic structure termed the Z-ring that recruits a hierarchy of fission related proteins early in the bacterial cell cycle. The interaction of FtsZ with ZapA drives its polymerisation and promotes FtsZ filament bundling thereby contributing to the spatio-temporal tuning of the Z-ring [1][2]. [1]. 15288790. The crystal structure of ZapA and its modulation of FtsZ polymerisation. Low HH, Moncrieffe MC, Lowe J;. J Mol Biol 2004;341:839-852. [2]. 12368265. A widely conserved bacterial cell division protein that promotes assembly of the tubulin-like protein FtsZ. Gueiros-Filho FJ, Losick R;. Genes Dev 2002;16:2544-2556. (from Pfam)

Gene:

zapA

Date:

2024-10-16

cell division protein ZapA interacts with FtsZ, a mid-cell cytokinetic structure termed the Z-ring that recruits a hierarchy of fission related proteins early in the cell cycle

Date:

2016-05-18