Protein Family Models

This is a family of ceramide beta-glucosyltransferases - EC:2.4.1.80. (from Pfam)

Date:

2024-08-14

Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis [1][2]. [1]. 9515923. Characterization of the gene cassette required for biosynthesis of the (alpha1-->6)-linked N-acetyl-D-mannosamine-1-phosphate capsule of serogroup A Neisseria meningitidis. Swartley JS, Liu LJ, Miller YK, Martin LE, Edupuganti S, Stephens DS;. J Bacteriol. 1998;180:1533-1539. [2]. 11953367. Novel Aeromonas hydrophila PPD134/91 genes involved in O-antigen and capsule biosynthesis. Zhang YL, Arakawa E, Leung KY;. Infect Immun. 2002;70:2326-2335. (from Pfam)

Date:

2024-10-16

Date:

2024-08-14

Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. (from Pfam)

Date:

2024-08-14

This family of genes include a glycosyl transferase, group 2 domain (PF00535) which are responsible, generally for the transfer of nucleotide-diphosphate sugars to substrates such as polysaccharides and lipids. The genes of this family are often found in the same genetic locus with squalene-hopene cyclase genes, and are never associated with genes for the metabolism of phytoene. Indeed, the members of this family appear to never be found in a genome lacking squalene-hopene cyclase (SHC), although not all genomes encoding SHC have this glycosyl transferase. In the organism Zymomonas mobilis the linkage of this gene to hopanoid biosynthesis has been noted and the gene named HpnB [1]. Hopanoids are known to feature polar glycosyl head groups in many organisms.

Gene:

hpnB

Date:

2019-09-10

HpnD is found regularly in a locus responsible for the biosynthesis of squalene from farnesyl diphosphate, and is now recognized to function as a presqualene diphosphate synthase (EC 2.5.1.103).

Gene:

hpnD

Date:

2021-08-25