Protein Family Models

This domain is found on many type IV pili methyl-accepting chemotaxis transducer proteins [1] where there is also a HAMP signature towards the C-terminus. It is a monomodular four-helix bundle and recognises nitrate and nitrite (Matilla et al. FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043). [1]. 24362261. Structure of Clostridium difficile PilJ exhibits unprecedented divergence from known type IV pilins. Piepenbrink KH, Maldarelli GA, de la Pena CF, Mulvey GL, Snyder GA, De Masi L, von Rosenvinge EC, Gunther S, Armstrong GD, Donnenberg MS, Sundberg EJ;. J Biol Chem. 2014;289:4334-4345. (from Pfam)

Date:

2024-10-16

Date:

2024-08-14

This is the dimerisation and phosphoacceptor domain of a sub-family of histidine kinases. It shares sequence similarity with Pfam:PF00512 and Pfam:PF07536. [1]. 10500846. The histidine protein kinase superfamily. Grebe TW, Stock JB;. Adv Microb Physiol 1999;41:139-227. (from Pfam)

Date:

2024-10-16

This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90. [1]. 18361456. Crystal structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source. Li Y, Bahti P, Shaw N, Song G, Chen S, Zhang X, Zhang M, Cheng C, Yin J, Zhu JY, Zhang H, Che D, Xu H, Abbas A, Wang BC, Liu ZJ;. Proteins 2008;71:2109-13. (from Pfam)

Date:

2024-10-16

Date:

2024-08-14

nitrate/nitrite two-component system sensor histidine kinase NarX acts as a sensor for nitrate/nitrite and transduces signal of nitrite/nitrate availability

Date:

2018-07-11

Gene:

narX

Date:

2022-10-11