Protein Family Models

This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity [2]. [1]. 8234324. Refined 1.8 A structure of human aldose reductase complexed with the potent inhibitor zopolrestat. Wilson DK, Tarle I, Petrash JM, Quiocho FA;. Proc Natl Acad Sci U S A 1993;90:9847-9851. [2]. 10884227. Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels. Gulbis JM, Zhou M, Mann S, MacKinnon R;. Science 2000;289:123-127. (from Pfam)

Date:

2024-10-16

aldo/keto reductase is a soluble NAD(P)(H) oxidoreductase that catalyzes the reduction of aldehydes and ketones to their corresponding primary and secondary alcohols, similar to Escherichia coli YajO, which functions as a 1-deoxyxylulose-5-phosphate synthase catalyzing the conversion of ribulose 5-phosphate (Ru5P) to 1-deoxy-D-xylulose 5-phosphate

Date:

2023-03-13