Protein Family Models for Protein (Select 501250769) - Protein Family Models

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Links from Protein

Items: 6

Select item 4115581.

Pyroglutamyl peptidase

Date:: 2024-08-14

Family Accession:: NF013624.5
Method:: HMM

Select item 3896632.

new record, indexing in progress

Family Accession:

Select item 3492523.

new record, indexing in progress

Family Accession:

Select item 1861684.

pyroglutamyl-peptidase I

Date:: 2020-10-26

Family Accession:: NF009676.0
Method:: HMM

Select item 1091445.

pyroglutamyl-peptidase I

pyroglutamyl-peptidase I (PGP-I) removes 5-oxoproline from various penultimate amino acid residues except L-proline

Date:: 2018-03-13

Family Accession:: 10793747
Method:: Sparcle

Select item 202906.

pyroglutamyl-peptidase I

Alternate names include pyroglutamate aminopeptidase, pyrrolidone-carboxylate peptidase, and 5-oxoprolyl-peptidase. It removes pyroglutamate (pyrrolidone-carboxylate, a modified glutamine) that can otherwise block hydrolysis of a polypeptide at the amino end, and so can be extremely useful in the biochemical studies of proteins. The biological role in the various species in which it is found is not fully understood. The enzyme appears to be a homodimer. It does not closely resemble any other peptidases.