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4a-hydroxytetrahydrobiopterin dehydratase
Pterin 4 alpha carbinolamine dehydratase is also known as DCoH (dimerisation cofactor of hepatocyte nuclear factor 1-alpha). [1]. 8897596. High-resolution structures of the bifunctional enzyme and transcriptional coactivator DCoH and its complex with a product analogue. Cronk JD, Endrizzi JA, Alber T;. Protein Sci 1996;5:1963-1972. (from Pfam)
4a-hydroxytetrahydrobiopterin dehydratase catalyzes the conversion from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin to (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin in tetrahydrobiopterin biosynthesis
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