Protein Family Models

This family represents the stationary-phase-induced ribosome-associated protein SRA also known as protein D. This protein was originally thought to be a ribosomal protein [1]. More recently it was shown that this is a ribosome hibernation factor that together with the factors Rmf, Hpf and RaiA is bound to the ribosomes during the onset and a few first days of the stationary phase when translation is strongly suppressed. In the prolonged stationary phase these factors dissociate from the ribosomes [2]. [1]. 11168583. Two proteins, YfiA and YhbH, associated with resting ribosomes in stationary phase Escherichia coli. Maki Y, Yoshida H, Wada A;. Genes Cells 2000;5:965-974. [2]. 36834540. Ribosome Protein Composition Mediates Translation during the Escherichia coli Stationary Phase. Reier K, Liiv A, Remme J;. Int J Mol Sci. 2023;24:3128. (from Pfam)

Date:

2024-10-16

Stationary phase-induced ribosome-associated protein (SRA) was previously known as RpsV or Protein D. It is one of a number of proteins that interact with ribosomes under nutrient-limiting conditions.

Gene:

sra

Date:

2020-10-26

Ribosomal_S22 domain-containing protein

Date:

2017-03-02